Traci Marin Curriculum Vitae

Cover Letter
Introduction
Education
Professional Experience
Credentials
Additional Experience
Scholastic Activities
Publications
Publications in Preparation
Professional Associations
Awards
Grants

COVER LETTER

Clinical Genomic Scientist - Metabolics

Search Committee

Invitae-Remote

Dear Search Committee Member:

As a results-oriented and motivated researcher, clinician and professor with rich scientific experience in the biomedical sciences such as genomics, metabolics, biology, biochemistry, and molecular biology, I would appreciate the opportunity to contribute to Invitae’s goals as a remote Clinical Genomic Scientist.

Highlights of my relevant background include:

Experience teaching healthcare, public health and biomedical science to community members, stakeholders, clients/patients, undergraduate students, and graduate students using both online and face-to-face platforms.
Proven ability to generate, analyze, and disseminate clinical and biological research information at the community and global level.
Publication and presentation history that includes next-generation sequencing, gene regulation and minute biochemical processes.
Experience as a program director and chair directly involved in faculty development and program administration at all levels.

I look forward to bringing my experience to benefit your operations. Should you need further information, I am available by phone, video conference or email. In the meanwhile, I look forward to the opportunity to speak with you at your earliest convenience.

Sincerely,

Traci Marin, Ph.D., M.PH., RRT, RPSGT

tracilmarin@gmail.com

760-887-2294

PROFESSOR | RESEARCHER

Accomplished clinician, academic, biomedical researcher, and dedicated community-health advocate with a history of success in leading cutting-edge biomedical research projects to provide valuable information to impact government and healthcare policy.
Natural leader adept at generating, implementing, and communicating epidemiological and biomedical research projects geared toward health initiatives and translation to the bedside.
Self-driven professional with a constant desire to learn new avenues to improve community health and client/patient advocacy, particularly at the genetic and biochemical level.

EDUCATION

Doctor of Philosophy in Biochemistry and Molecular Biology, 2013
- Dissertation: AMPK regulates an epigenetic metabolome
- University of California, Riverside, California
Master of Science in Biochemistry and Molecular Biology, 2010
- University of California, Riverside, California
Master of Public Health in Epidemiology and Biostatistics, 2003
- Thesis: Algorithm to predict exercise-induced hypoxemia in chronic obstructive lung disease
- Loma Linda University, Loma Linda, California
Bachelor of Science in Emergency Medical Care, 2000
- Loma Linda University, Loma Linda, California
Associate of Science in Respiratory Therapy, 1992
- Victor Valley College, Victorville, California

RELEVANT PROFESSIONAL EXPERIENCE

INSTITUTE OF ENGINEERING AND MEDICINE VISITING SCHOLAR (2013 to Present)
- University of California, San Diego, San Diego, California
  - Biomedical researcher specializing in genomics, metabolomics, biology, biochemistry, microbiology, molecular biology, bioinformatics, systems biology, biostatistics, bioengineering, and animal research as they translate to the bedside.
PROGRAM DIRECTOR, CHAIR AND PROFESSOR (2002 to Present)
- Victor Valley College, Victorville, California
  - Passionate and research-minded Program Director of the Respiratory Therapy Program; direct all administrative and educational aspects including fiscal planning, continuous program design, implementation, review and revision, and marketing at the community and industry levels. Courses taught include a range of subjects from microbiology, biology, chemistry, pharmacology, Yoga, polysomnography, respiratory therapy, to more specialized neonatal and pediatric respiratory care.
TRANQUILITY COMMUNITY HEALTH, FOUNDER (2002 to Present)
- Community health advocacy through development and implementation of community health programs and educational avenues geared toward bringing biomedical science to the everyday person. https://tranquilitycommunityhealth.wordpress.com/about/
SCHOOL OF MEDICINE, ASSOCIATE RESEARCH PROFESSOR,PROGRAM DIRECTOR (2013 to 2018)
- Award-winning biomedical researcher and professor, specializing in genomics, biochemistry, molecular biology, bioinformatics, systems biology, biostatistics, bioengineering, and animal research as they translate to the bedside. Ongoing interest in grant-writing, motivating and mentoring students. Strong track record in teaching epigenetics, metabolism, and cardiopulmonary and neuronal function, disease pathophysiology, and therapeutic interventions.
- Spearheaded Allied Health, Cardiopulmonary Science Graduate Program for on-campus and remote students. Proactively directed curriculum development, implementation and assessment, as well as administration of budget. Instrumental in leading and advising Dissertation Committees and mentoring clinical and academic students, with a strong knowledge of the accreditation process. Oversaw cutting-edge health science and biomedical research. Taught 30 courses related to biological, health and biomedical translational science.

CREDENTIALS

Registered Respiratory Therapist (RRT) CA RCP license #16687
Registered Polysomnography Technician (RPGST) #12948
Polysomnography Certificate 2008

ADDITIONAL RELEVANT EXPERIENCE

Course reviewer and editor for a spectrum of biological, biostatistics and health science courses for publishers such as Elsevier and Pearson. Freedom Learning Group. (2018 to Present).
Webinar speaker and editor for a spectrum of biological, bioinformatics, biostatistics and health science courses, review articles and research articles. Enago Academy and Edanz. (2018 to Present).
Education course writer, reviewer and editor for Healthcare professions, Western Schools, Boston, MA (2014 to 2018). Continuing. List of available authored courses available upon request.
Registered Respiratory Therapist and Training Center Coordinator, J. L. Pettis VAMC, Loma Linda, CA (1991 to 2005).

SCHOLASTIC ACTIVITIES

Third European Workshop on AMPK, Ile De Porquerolles, France, 2017
School of Allied Health Professions Research Symposium Loma Linda University, 2017
California Thoracic Society Seminars: AMPK epigenetically regulates ventilatory pattern in response to oxidative stress. Carmel, Ca. 2017
Carefusion Clinical Trail, FDA Level, confidential, current.
Lunch and Learn, County of San Bernardino - Children and Family Services. San Bernardino, CA. Lead exercise on how strategic nutrition and quality sleep can keep inflammation and oxidative stress (free-radical cell damage) at bay, January 2014 to Present, Monthly
Basic Science Symposium, Loma Linda University, Loma Linda, CA, 2015
Epigenetics and Health Conference, California State University, San Bernardino, CA, 2015
Inland Empire Dental Conference, on Metabolism and Sleep Health, San Bernardino, CA, 2014
Epigenetics and Mitochondrial Function, University of San Diego, San Diego, CA, 2012
National Institute of Health, AMPK and Anti-inflammatory Effects through PARP1 and BCL-6, Bethesda, MD, 2012
Aegaen Conference on Pathways, networks, and systems medicine, AMPK regulates and Epigenetic Network, Crete, Greece, 2011.
Experimental Biology Conference, Mass Spectroscopy and AMPK Targets, Anaheim, CA, 2010

PUBLICATIONS

Gongol B, Marin T, Zhang J, et al. Shear Stress Regulation of miR-93 and miR-484 Maturation through Nucleolin. PNAS 2019 Accepted for publication.
Gongol B, Sari I, Bryant T, Rosete G, Marin T. AMPK: An Epigenetic Landscape Modulator. Int J Mol Sci. 2018
Zang J, Dong J, Martin M, He M, Gongol B, Marin TL, et al. AMPK Phosphorylation of ACE2 in Endothelium Mitigates Pulmonary Hypertension. Am J Respir Crit Care Med. 2018
Gongol B, Marin T* et al. Cellular hermetic response to 27-hydroxycholesterol promotes neuroprotection through AICD induction of MAST4 abundance and kinase activity. Scientific Reports, 2017 *Co-first author
Gongol B, Marin T, et al. Systems Approach to Identifying Kinase Targets. Chapter in AMPK protocols for the Methods in Molecular Biology series. Spring International Publishing. 2018 (Accepted for publication 2017).
Marin TL, Gongol B, Zhang F, Martin M, Johnson DA, Xiao H, Wang Y, Subramaniam S, Chien S, Shyy J. AMPK Activation Regulates a Metabolic Transcriptome through DNMT1, RBBP7, and HAT1. Science Signaling, 2017.
Shentu TP, He M, Sun X, Zhang J, Zhang F, Gongol B, Marin TL, Zhang J, Wen L, Wang Y, Geary GG, Zhu Y, Johnson DA, Shyy JY. AMP-Activated Protein Kinase and Sirtuin 1 Coregulation of Cortactin Contributes to Endothelial Function. Arterioscler Thromb Vasc Biol., 2016.
Gongol BR, Rosete GT, Alyami BH, Singh RK, Galech S, Marin TL. Hyperbaric Oxygen Induced Vitamin D Receptor and ROS Responsive Genes: A Bioinfor- matic Analysis. JSM Biotechnol Bioeng., 2016.
Shang F, Zhang J, Li Z, Zhang J, Yin Y, Wang Y, Marin TL, Gongol B, Xiao H, Zhang YY, Chen Z, Shyy JY, Lei T.Cardiovascular Protective Effect of Metformin and Telmisartan: Reduction of PARP1 Activity via the AMPK-PARP1 Cascade. PLoS One, 2016.
Marin TL, Gongol B, Martin M, King SJ, Smith L, Johnson JA, Subramaniam S, Chien S, Shyy J. Identification of AMP-activated protein kinase targets by a consensus sequence search of the proteome. BMC, 2013.
Alanshwan A, Hakamy A, Gongol B, Alismail A, Horn M, Marin TL. Exhaled Biomarkers of Oxidative Stress and Inflammation in Hookah Smokers: A Public Health Concern. Gratis J Cancer Biology and Therapeutics, 2015.
Xiao H, Lu M, Lin TY, Chen Z, Chen G, Wang WC, Marin T, Shentu TP, Wen L, Gongol B, Sun W, Liang X, Chen J, Huang HD, Pedra JH, Johnson DA, Shyy JY. SREBP2 Activation of NLRP3 Inflammasome in Endothelium Mediates Hemodynamic-Induced Atherosclerosis Susceptibility. Circulation, 2013.
Marin T, Gongol B, Chen Z, Woo B, Subramaniam S, Chien S, Shyy JY. Mechanosensitive microRNAs - Role in Endothelial Responses to Shear Stress and Redox State FRBM, 2013.
Gongol B, Marin T, Peng IC, Woo B, Martin M, King S, Sun W, Johnson DA, Chien S, Shyy JY. AMPKÎ±2 exerts its anti-inflammatory effects through PARP-1 and Bcl-6. PNAS, 2012. Co-first author
Peng IC, Chen Z, Sun W, Li YS, Marin TL, Hsu PH, Su MI, Cui X, Pan S, Lytle CY, Johnson DA, Blaeser F, Chatila T, Shyy JY. Glucagon regulates ACC activity in adipocytes through the CaMKKÎ²/AMPK pathway. AJP-Endocrinology and Metabolism, 2012.
Marin T, Gongol B, Shyy J. AMPK regulates PGC-1Î± through epigenetic mechanisms. Abstract. 9th International Conference on Networks, Pathways, and Systems Medicine, 2011.
Marin T, Gongol B. Shyy J. AMPK Targets: Predicted by Mass Spectroscopy and Proteomic Sequence Mapping. FASEB, 2010.
Wilkins, Krider, Sheldon. Chapter 10: Bedside Interpretation of Electrocardiogram. Clinical Assessment in Respiratory Care 5th ed., 2005.
Book Review: The Respiratory System: Basic Science and Clinical Conditions. Andrew Davies PhD DSc and Carl Moores BA BSc MB CHB. (Systems of the Body Series) Softcover, illustrated, 197 pages. Edinburgh Uk: Churchill Livingston/Elsevier Science; 2003. Printed in Respiratory Care September 2004, vol. 49, Number 9.
Review of EMS scenario outline for book proposal for Prentice Hall/Health Brady Person Education in March 2003.
Wilkins, Marin, Marshak. Instructor’s Curriculum Resource for Egan’s Fundamentals 8th ed. Mosby. 2003
Article Review: Stoller, Orens, Faticia, Weekly vs. daily changes of in-line suction catheter and impact on rates of ventilator-acquired pneumonia and associated cost. Resp. Care. May 2003 vol. 48, 2002.
Review of Wilderness EMC book outline and power point for Prentice Hall/Health Brady Person Education in September. 2003.

PUBLICATIONS UNDER REVIEW AND PREPARATION

Yan, J, Gongol, B, Marin, T, et al. c-Myc and AMPK Control Cell Proliferation by Regulating TDG-Mediated DNA Demethylation.
Gongol B, Bravo S, Lo T, Soriano S, Shyy J, Marin TL. Angiogenenin is a nucleolin adaptor protein eliciting an AMPK mediated molecular switch: pro-angiogenic effects of hyperbaric oxygen therapy.
Gongol B, Galech S, Soriano S, Shyy J, Marin TL. The AICD, TIP60, FE65 complex association mediates cell migration and invasion by increasing synaptojanin 2 expression.
Gongol B, Soriano S, Wilson C, Shyy J, Marin TL. AMPK modulates ventilatory pattern through the CYSTLR2-PHOX2b pathway.

PROFESSIONAL ASSOCIATIONS

American Academy of Sleep Medicine
American Lung Association
America Association for Respiratory Care

AWARDS

Young Investigator Award, Loma Linda University (2016)
Distinguished Alumni Award, Loma Linda University (2015)
Magna Cum Laude, University of California Riverside (2013)
Mary T. Wedding Travel Award, University of California Riverside (2009)
President’s Award, Loma Linda University (2000)

GRANTS

Project Encompass, an interdisciplinary and transdisciplinary approach to wound care at Loma Linda University. 2017-2018
Loma Linda University GRASP award (intramural), AMP-activated protein kinase (AMPK) regulates an epigenetic network in respiratory pattern response to inflammation and mitochondrial redox imbalance. 2015-2017
Loma Linda University GRASP award (intramural), Hyperoxia and hypoxia regulated angiogenesis under HBOT. 2014-2016